Jan Martin Berke : rechercher sur Z-Library

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1

Hepatitis C virus comes full circle: Production of recombinant infectious virus in tissue culture

Jan Martin Berke, Darius Moradpour

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 132 KB

english, 2005

2

Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Dr. Maxwell D. Cummings, Dr. Tse-I Lin, Lili Hu, Dr. Abdellah Tahri, David McGowan, Dr. Katie Amssoms, Stefaan Last, Dr. Benoit Devogelaere, Marie-Claude Rouan, Dr. Leen Vijgen, Dr. Jan Martin Berke,

Journal:

Angewandte Chemie

Année:

2012

Langue:

english

Fichier:

PDF, 713 KB

english, 2012

3

Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Dr. Maxwell D. Cummings, Dr. Tse-I Lin, Lili Hu, Dr. Abdellah Tahri, David McGowan, Dr. Katie Amssoms, Stefaan Last, Dr. Benoit Devogelaere, Marie-Claude Rouan, Dr. Leen Vijgen, Dr. Jan Martin Berke,

Journal:

Angewandte Chemie International Edition

Année:

2012

Langue:

english

Fichier:

PDF, 720 KB

english, 2012

4

Development of a high-content screening assay to identify compounds interfering with the formation of the hepatitis C virus replication complex

Jan Martin Berke, Denis Fenistein, Frederik Pauwels, Rob Bobbaers, Oliver Lenz, Tse-I. Lin, Eberhard Krausz, Gregory Fanning

Journal:

Journal of Virological Methods

Année:

2010

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2010

5

Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series

David McGowan, Sandrine Vendeville, Tse-I Lin, Abdellah Tahri, Lili Hu, Maxwell D. Cummings, Katie Amssoms, Jan Martin Berke, Maxime Canard, Erna Cleiren, Pascale Dehertogh, Stefaan Last, Els Fransen,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2012

6

2′-Deoxy-2′-spirocyclopropylcytidine Revisited: A New and Selective Inhibitor of the Hepatitis C Virus NS5B Polymerase

Jonckers, Tim H. M., Lin, Tse-I, Buyck, Christophe, Lachau-Durand, Sophie, Vandyck, Koen, Van Hoof, Steven, Vandekerckhove, Leen A. M., Hu, Lili, Berke, Jan Martin, Vijgen, Leen, Dillen, Lieve L. A.,

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2010

7

Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

Cummings, Maxwell D., Lin, Tse-I, Hu, Lili, Tahri, Abdellah, McGowan, David, Amssoms, Katie, Last, Stefaan, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascal

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2014

8

Virologic response and characterisation of HCV genotype 2–6 in patients receiving TMC435 monotherapy (study TMC435-C202)

Lenz, Oliver, Vijgen, Leen, Berke, Jan Martin, Cummings, Maxwell D., Fevery, Bart, Peeters, Monika, Smedt, Goedele De, Moreno, Christophe, Picchio, Gaston

Journal:

Journal of Hepatology

Année:

2013

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2013

9

Nucleotide Prodrugs of 2′-Deoxy-2′-spirooxetane Ribonucleosides as Novel Inhibitors of the HCV NS5B Polymerase

Jonckers, Tim H. M., Vandyck, Koen, Vandekerckhove, Leen, Hu, Lili, Tahri, Abdellah, Van Hoof, Steven, Lin, Tse-I, Vijgen, Leen, Berke, Jan Martin, Lachau-Durand, Sophie, Stoops, Bart, Leclercq, Laure

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 437 KB

english, 2014

10

Discovery of 1-((2R,4aR,6R,7R,7aR)-2-isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3’-5’-Cyclic Phosphate Ester Prodrug of 2’-Deoxy-2’-Spirooxetane Uridine Triphosphate useful for HCV Inhibition.

Jonckers, Tim H.M., Tahri, Abdellah, Vijgen, Leen, Berke, Jan-Martin, Lachau-Durand, Sophie, Stoops, Bart, Snoeys, Jan, Leclercq, Laurent, Tambuyzer, Lotke, Lin, Tse-I, Simmen, Kenny, Raboisson, Pierr

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1023 KB

english, 2016

11

Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro

Berke, Jan Martin, Tan, Ying, Verbinnen, Thierry, Dehertogh, Pascale, Vergauwen, Karen, Vos, Ann, Lenz, Oliver, Pauwels, Frederik

Journal:

Antiviral Research

Année:

2017

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2017

12

Capsid assembly modulators have a dual mechanism of action in primary human hepatocytes infected with hepatitis B virus

Berke, Jan Martin, Dehertogh, Pascale, Vergauwen, Karen, van Damme, Ellen, Mostmans, Wendy, Vandyck, Koen, Pauwels, Frederik

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2017

13

Synthesis and Evaluation of N-phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators inhibiting Hepatitis B Virus (HBV).

Vandyck, Koen, Rombouts, Geert, Stoops, Bart, Tahri, Abdellah, Vos, Ann, Verschueren, Wim, Wu, Yiming, Yang, Jingmei, Hou, Fuliang, Huang, Bing, Vergauwen, Karen, Dehertogh, Pascale, Berke, Jan-Martin

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 718 KB

english, 2018

14

Novel potent capsid assembly modulators regulate multiple steps of the Hepatitis B virus life-cycle

Lahlali, Thomas, Berke, Jan Martin, Vergauwen, Karen, Foca, Adrien, Vandyck, Koen, Pauwels, Frederik, Zoulim, Fabien, Durantel, David

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2018

15

Pharmacokinetics, Safety and Tolerability of JNJ-56136379, a Novel Hepatitis B Virus Capsid Assembly Modulator, in Healthy Subjects

Vandenbossche, Joris, Jessner, Wolfgang, van den Boer, Maarten, Biewenga, Jeike, Berke, Jan Martin, Talloen, Willem, De Zwart, Loeckie, Snoeys, Jan, Yogaratnam, Jeysen

Journal:

Advances in Therapy

Année:

2019

Langue:

english

Fichier:

PDF, 837 KB

english, 2019

16

Indolylglycines backbones in the synthesis of enantiopure 3,3-spiroindolenines, indolyl tetracyclic hemiaminals and 3-indolyl-maleimides frameworks

Markus, Jozef, Ferko, Branislav, Berkeš, Dušan, Moncol, Ján, Lawson, Ata Martin, Othman, Mohamed, Daïch, Adam

Journal:

European Journal of Organic Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2019

17

Indolylglycines backbones in the synthesis of enantiopure 3,3-spiroindolenines, indolyl tetracyclic hemiaminals and 3-indolyl-maleimides frameworks

Markus, Jozef, Ferko, Branislav, Berkeš, Dušan, Moncol, Ján, Lawson, Ata Martin, Othman, Mohamed, Daïch, Adam

Journal:

European Journal of Organic Chemistry

Année:

2019

Fichier:

PDF, 2.36 MB

2019

18

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation

Wang, Shishan, Fogeron, Marie-Laure, Schledorn, Maarten, Dujardin, Marie, Penzel, Susanne, Burdette, Dara, Berke, Jan Martin, Nassal, Michael, Lecoq, Lauriane, Meier, Beat H., Böckmann, Anja

Journal:

Frontiers in Molecular Biosciences

Année:

2019

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2019

19

FRI-188-Sequence analysis of baseline and on-treatment samples from HBV-infected chronic hepatitis B patients treated for 28 days with JNJ-56136379 monotherapy

Verbinnen, Thierry, Hodari, Moana, Talloen, Willem, Berke, Jan Martin, Blue, David, Yogaratnam, Jeysen, Shukla, Umesh, Meyer, Sandra De, Lenz, Oliver

Journal:

Journal of Hepatology

Année:

2019

Fichier:

PDF, 461 KB

2019

20

Correction to: Pharmacokinetics, Safety and Tolerability of JNJ-56136379, a Novel Hepatitis B Virus Capsid Assembly Modulator, in Healthy Subjects

Vandenbossche, Joris, Jessner, Wolfgang, van den Boer, Maarten, Biewenga, Jeike, Berke, Jan Martin, Talloen, Willem, De Zwart, Loeckie, Snoeys, Jan, Vandyck, Koen, Fry, John, Yogaratnam, Jeysen

Journal:

Advances in Therapy

Année:

2020

Fichier:

PDF, 183 KB

2020

21

Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379

Berke, Jan Martin, Dehertogh, Pascale, Vergauwen, Karen, Mostmans, Wendy, Vandyck, Koen, Raboisson, Pierre, Pauwels, Frederik

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2020

Fichier:

PDF, 3.74 MB

2020

22

Anti-HBV activity of the HBV capsid assembly modulator JNJ-56136379 across full-length genotype AâH clinical isolates and core site-directed mutants in vitro

Verbinnen, Thierry, Tan, Ying, Wang, Gengyan, Dehertogh, Pascale, Vergauwen, Karen, Neefs, Jean-Marc, Jacoby, Edgar, Lenz, Oliver, Berke, Jan Martin

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2020

Fichier:

PDF, 524 KB

2020

23

Adherence and acceptability of a robot-assisted Pivotal Response Treatment protocol for children with autism spectrum disorder

van den Berk-Smeekens, Iris, van Dongen-Boomsma, Martine, De Korte, Manon W. P., Den Boer, Jenny C., Oosterling, Iris J., Peters-Scheffer, Nienke C., Buitelaar, Jan K., Barakova, Emilia I., Lourens, T

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 1.25 MB

2020

24

Virology analysis of chronic hepatitis B infected patients treated for 28 days with JNJâ56136379 monotherapy

Verbinnen, Thierry, Hodari, Moana, Talloen, Willem, Berke, Jan Martin, Blue, David, Yogaratnam, Jeysen, Vandenbossche, Joris, Shukla, Umesh, De Meyer, Sandra, Lenz, Oliver

Journal:

Journal of Viral Hepatitis

Année:

2020

Fichier:

PDF, 669 KB

2020

25

Self-initiations in young children with autism during Pivotal Response Treatment with and without robot assistance

De Korte, Manon WP, van den Berk-Smeekens, Iris, van Dongen-Boomsma, Martine, Oosterling, Iris J, Den Boer, Jenny C, Barakova, Emilia I, Lourens, Tino, Buitelaar, Jan K, Glennon, Jeffrey C, Staal, Wou

Journal:

Année:

2020

Fichier:

PDF, 361 KB

2020

26

The Effects of Long-Term ChildâRobot Interaction on the Attention and the Engagement of Children with Autism

van Otterdijk, Maria T. H., de Korte, Manon W. P., van den Berk-Smeekens, Iris, Hendrix, Jorien, van Dongen-Boomsma, Martine, den Boer, Jenny C., Buitelaar, Jan K., Lourens, Tino, Glennon, Jeffrey C.,

Journal:

Année:

2020

Fichier:

PDF, 1.41 MB

2020